Associate Professor
GAO Ruijuan
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time：2021-12-02
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Name：GAO Ruijuan
Department：Department of Oncology
Tel: (8610)83167179；13269093108
Email: gaoruijuan@imb.cams.cn
Education & Research Experience
2020/09-2021/09 Associate director, Xinjiang Key Laboratory of Uighur Medicines, Xinjiang Institute of Materia Medica
2018/02-2019/08 Associate research scientist, Yale school of Medicine, New Haven, Connecticut, USA
2016/08-2018/02 Visiting scholar, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
2013/09 – present Associate professor, Institute of Medicinal Biotechnology, Chinese Academy of Medical Science (CAMS) & Peking Union Medical College (PUMC)
2006/08 - 2013/09 Assistant professor, Institute of Medicinal Biotechnology, CAMS & PUMC
2003/08 - 2006/07 Ph.D. in microbial and biochemical pharmacy, CAMS & PUMC
Research Field
Study on the novel antitumor and anti-pulmonary fibrosis drugs
Research Interests
Dr. Gao has been mainly engaged in the study of novel antitumor drugs derived from medicinal microorganisms and/or based on nano-technology as well as the new anti-pulmonary fibrosis drugs. The research interests include: 1) Research on the novel antitumor drugs obtained from medicinal microorganisms, such as antitumor antibiotics, antibody-based fusion proteins, etc.; 2) Study on the new and tumor-targeted nanoparticle delivery system; 3) Research on the anti-pulmonary fibrosis drugs and new molecular mechanisms of lung fibrosis.
Selected Publications
1. Gao RJ, Peng XY, Perry C, Sun HX, Ntokou A, Ryu C, Gomez JL, Reeves BC, Walia A, Kaminski N, Neumark N, Ishikawa G, Black KE, Hariri LP, Moore MW, Gulati M, Homer RJ, Greif DM, Eltzschig HK, Herzog EL*. Macrophage-derived netrin-1 drives adrenergic nerve-associated lung fibrosis. J Clin Invest 2021; 131(1): e136542.
2. Gao RJ#, Mitra RN#, Zheng M, Wang K, Dahringer JC, Han ZC*. Developing nanoceria-based pH-dependent cancer-directed drug delivery system for retinoblastoma. Adv Funct Mater 2018, 28(52): 1806248.
3. Gao RJ*, Li L, Shang BY, Zhao CY, Sheng WJ, Li DD. A gelatinases-targeting scFv-based fusion protein shows enhanced antitumour activity with Endostar against hepatoma. BCPT 2015, 117(2): 105-116.
4.Mitra RN, Gao RJ, Zheng M, Wu MJ, Voinov MA, Smirnov AI, Smirnova TI, Wang K, Chavala S, Han ZC*. Glycol chitosan engineered autoregenerative antioxidant significantly attenuates pathological damages in models of age-related macular degeneration. ACS Nano 2017, 11(5): 4669-4685.
Awards and Honors
2019 Third prize of pharmacy group of the 14th National Youth Science and Technology Forum on medicine and health
2010 The third prize of outstanding academic papers in the column of the National Science and Technology Major Projects of China in 2010 awarded by the editorial committee of Chinese Journal of New Drugs
2005 “Excellent Postgraduates” of CAMS & PUMC
